Risk Factors for Development of Pneumatosis Intestinalis after Pediatric Hematopoietic Stem Cell Transplantation: A Single-Center Case-Control Study

Polina Frolova Gregory,Jonathan Angus, Adam W. Brothers,Ashley N. Gray,Kristina Skeen,Ted Gooley,Chris Davis,Helen H.R. Kim,Scott J. Weissman,Hengqi Betty Zheng,Kanwaldeep Mallhi,K. Scott Baker

Transplantation and Cellular Therapy（2022）

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摘要

•The risk for pneumatosis intestinalis (PI) increases in patients with acute gastrointestinal graft-versus-host disease receiving steroids.•The risk for PI increases with supplemental nasogastric tube feeds.•Asymptomatic PI may be self-limiting.•Computed tomography imaging is not necessary for diagnosing PI.•Clinical improvement should outweigh follow-up imaging when resuming diet.

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关键词

Pneumatosis intestinalis,Pneumoperitoneum,Stem cell transplantation,Gastrointestinal graft-versus-host disease,Steroids,Nasogastric tube feeding

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