Understanding the Pivotal Role of the Vagus Nerve in Health from Pandemics

BIOENGINEERING-BASEL(2022)

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摘要
The COVID-19 pandemic seems endless with the regular emergence of new variants. Is the SARS-CoV-2 virus particularly evasive to the immune system, or is it merely disrupting communication between the body and the brain, thus pre-empting homeostasis? Retrospective analysis of the COVID-19 and AIDS pandemics, as well as prion disease, emphasizes the pivotal but little-known role of the 10th cranial nerve in health. Considering neuroimmunometabolism from the point of view of the vagus nerve, non-invasive bioengineering solutions aiming at monitoring and stimulating the vagal tone are subsequently discussed as the next optimal and global preventive treatments, far beyond pandemics.
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关键词
pandemics, COVID-19, HIV, prion, non-invasive vagus nerve stimulation, neuroimmunometabolism
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