Examination of Abnormal Alpha-synuclein Aggregates in the Enteric Neural Plexus in Patients with Ulcerative Colitis.

Noriaki Gibo,Tomonari Hamaguchi,Yasuo Miki,Takeshi Yamamura,Masato Nakaguro,Mikako Ito,Masanao Nakamuara,Hiroki Kawashima,Masaaki Hirayama,Yoshiki Hirooka,Koichi Wakabayashi,Kinji Ohno

Journal of gastrointestinal and liver diseases : JGLD（2022）

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摘要

Omission of epitope exposure enabled us to immunostain aggregated αSyn in the colon by pSyn#64 with low nonspecific staining, but the number of 23 UC patients was not high enough to discern whether abnormal αSyn aggregation in the colonic neural plexus was increased in UC or not.

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关键词

Parkinson's disease,alpha-synuclein,p62,ulcerative colitis,enteric neural plexus

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