PTBP3 promotes tumorigenesis of glioblastoma by stabilizing Twist1

Peng Xie, Yueqing Zhang,Rui Chen,Jinyu Zheng,Gang Cui

Translational Oncology(2022)

引用 2|浏览15
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摘要
•PTBP3 is upregulated in GBM and predicts poor prognosis.•PTBP3 promotes proliferation, EMT, migration, and invasion of GBM.•PTBP3 stabilizes Twist1 by decreasing its ubiquitination and degradation.
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关键词
PTBP3,Tumorigenesis,Ubiquitination,Twist1,GBM
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