Desonide Nanoemulsion Gel for Transdermal Absorption Drug Delivery: Pharmacodynamic and Safety Evaluation.

Nanoemulsion gel can be applied to improve the efficacy of drugs with low potency or poor solubility. DES NE gel provides the higher transdermal potential than other delivery systems. In this study, it was found that nano-emulsion gel is a promising percutaneous carrier of DES. DES NE-GEL has significant curative effect on dermatitis/eczema in mouse model, and is expected to provide a new, efficient and low toxic preparation for clinical treatment of dermatitis/eczema through percutaneous system.