Long-term follow-up and liver outcomes in children with cystic fibrosis and nodular liver on ultrasound in a multi-center study.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society（2022）

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摘要

NOD developed clinically evident portal hypertension faster than NL without worse growth or lung disease.

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关键词

ALT, alanine aminotransferase,APRI, aspartate aminotransferase to platelet ratio index,AST, aminotransferase,CAP, continuous attenuation parameter,CFRD, cystic-fibrosis-related diabetes,CFTR, cystic fibrosis transmembrane regulator,Cirrhosis,Cystic fibrosis liver disease,FEV1, forced expiratory volume in one second,FIB4, fibrosis index based on four factors,FVC, forced vital capacity,GGT, gamma-glutamyl transferase,IGT, impaired glucose tolerance,INR, international normalized ratio,LSM, liver stiffness measurement,NL, normal,NOD, nodular,PELD, pediatric end-stage liver disease,PUSH, prediction by ultrasound of the risk of hepatic cirrhosis,US, ultrasound,Ultrasound,VCTE, vibration controlled transient elastography,WBC, white blood cell count,abbreviations: CF, cystic fibrosis

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