Evolution and Transmission of Cefiderocol-Resistant Acinetobacter baumannii During an Outbreak in the Burn Intensive Care Unit.

Steven M Smoke,Alison Brophy,Samuel Reveron,Alina Iovleva,Ellen G Kline,Michael Marano,Lincoln P Miller,Ryan K Shields

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America（2023）

引用 17|浏览6

暂无评分

摘要

We report on 11 critically ill burn patients treated with cefiderocol for carbapenem-resistant Acinetobacter baumannii infections. Clinical success was achieved in 36% and complicated by treatment-emergent resistance and interpatient transmission of cefiderocol-resistant A. baumannii. Resistant isolates harbored disrupted pirA and piuA genes that were not disrupted among susceptible isolates.

查看译文

关键词

antibiotic resistance,burn,carbapenem-resistant Acinetobacter baumannii,cefiderocol,whole-genome sequencing

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要