Doravirine-associated resistance mutations in antiretroviral therapy naïve and experienced adults with HIV-1 subtype C infection in Botswana

Journal of Global Antimicrobial Resistance（2022）

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摘要

•Lower DOR-resistance in ART-naïve versus ART-experienced individuals with VF.•DOR-resistance was higher among individuals failing NNRTI-containing regimens.•DOR use in NNRTI-experienced population should be based on HIV drug resistance data.

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关键词

HIV-1C,Drug resistance mutations,Antiretroviral (ART) experienced,Antiretroviral (ART) naive,Doravirine,Botswana

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