Reassessing vascular endothelial growth factor (VEGF) in anti-angiogenic cancer therapy

Tobiloba C Elebiyo, Damilare Rotimi,Ikponmwosa O Evbuomwan,Rotdelmwa Filibus Maimako,Matthew Iyobhebhe,Oluwafemi Adeleke Ojo,Olarewaju M Oluba,Oluyomi S Adeyemi

Cancer Treatment and Research Communications（2022）

引用 18|浏览6

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摘要

•The role of tumor angiogenesis in tumor growth, metastasis, and drug resistance.•VEGF, VEGFRs, and their inhibitors could glean newer options such as vascular normalization, to enhance anti-angiogenic cancer therapy.•The vascular normalization therapy could be a promising strategy in combating cancer.

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关键词

Cancer,Tumour blood vessels,Angiogenesis,Vascular endothelial growth factor (VEGF),Anti-angiogenic therapy,Vascular normalization therapy

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