Characterization of Plasma Immunoglobulin G Responses in Elite Neutralizers of Human Cytomegalovirus.

Melissa J Harnois,Maria Dennis,Dagmar Stöhr,Sarah M Valencia,Nicole Rodgers,Eleanor C Semmes,Helen S Webster,Jennifer A Jenks,Richard Barfield,Justin Pollara,Cliburn Chan,Christian Sinzger,Sallie R Permar

The Journal of infectious diseases（2022）

引用 3|浏览23

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摘要

We conclude that antibody responses against multiple glycoprotein specificities may be needed to achieve potent plasma neutralization and that potently HCMV elite-neutralizing plasma antibodies can also mediate polyfunctional responses.

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关键词

elite neutralizers,human cytomegalovirus,neutralizing antibodies,polyfunctional antibodies

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