The long noncoding RNA LINC00200 promotes the malignant progression of MYCN-amplified neuroblastoma via binding to insulin like growth factor 2 mRNA binding protein 3 (IGF2BP3) to enhance the stability of Zic family member 2 (ZIC2) mRNA

Pathology - Research and Practice(2022)

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摘要
Overall, we showed that LINC00200 was upregulated in NB tissues and the LINC00200/IGF2BP3/ZIC2 regulatory axis might be the possible therapeutic target for NB.
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关键词
Neuroblastoma (NB),LINC00200,RNA binding protein (RBP),Malignant progression
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