Immature tertiary lymphoid structure formation was increased in the melanoma tumor microenvironment of IKZF1 transgenic mice.

Translational cancer research（2022）

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摘要

does not affect the proliferation of melanoma cells. Transgenic mice overexpressing were successfully constructed. is a key driver gene of the formation of immature TLS.

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关键词

IKZF1,melanoma,tertiary lymphoid structure (TLS),tumor immune microenvironment

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