Pulmonary Function and Respiratory Diseases in Different Genotypes of Alpha-1 Antitrypsin Deficiency.

José María Hernández Pérez, Juan José Suárez Sánchez,Claudia Viviana López Charry,Yolanda Ramallo Fariña,José Antonio Pérez Pérez

Turkish thoracic journal（2022）

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摘要

The PI*ZZ and PI*SS genotypes seem to be associated with the prevalence of chronic obstructive pulmonary disease. Tobacco use, low body weight, and older age are risk factors that increase the probability of prevalence of chronic obstructive pulmonary disease by up to 70% in PI*MZ individuals.

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关键词

Alpha-1 antitrypsin deficiency, spirometry, lung function, chronic obstructive pulmonary disease, respiratory disease

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