Rh(III)‐Catalyzed C6‐Selective C−H 3‐Oxoalkylation of 2‐Pyridones with Allylic Alcohols

Rhodium(III)-catalyzed C6-selective C-H 3-oxoalkylation of 2-pyridones was developed with commercially available allylic alcohols as the 3-oxoalkyl sources. In this reaction, the excellent site selectivity was controlled by the 2-pyridyl directing group on the nitrogen of the pyridone ring. This reaction features good functional group tolerance and the generation of 6-(3-oxoalkyl) pyridones in moderate to good yields.