Single-Atom Nanocatalysts for Biosensing Application

Single-atom (SA) catalysts, as a rising star in the catalytic field, have many advantages over traditional nanocatalysts. SA catalysts have improved catalytic activity, a simple and tunable structure, and obvious active sites, which might provide a good opportunity for biosensing technique innovation. This paper will review the latest research progress of SA catalysts in the biosensing field. In particular, we will emphasize on the biosensing strategies for the determination of disease-related biological matrices (H2O2, biological enzyme, NO) and environmental pollutants (organophosphorus pesticides, heavy metal ions, and volatile organic compounds). Finally, we will provide some perspective and discuss the challenges that SA catalysts continue to face.