Multifunctional membranes for lipidic nanovesicle capture

Simona Salerno,Sabrina Morelli,Antonella Piscioneri, Mariangela Frangipane,Alessandro Mussida,Laura Sola,Roberto Frigerio,Alessandro Strada,Greta Bergamaschi,Alessandro Gori,Marina Cretich,Marcella Chiari,Loredana De Bartolo

Separation and Purification Technology（2022）

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摘要

•Chemoselective membrane functionalization for lipidic nanovesicle capture and release.•Polysulfone membrane nanometric coating of copolymers with different functionalities.•Copolymer functionalities enable sensing peptide conjugation by click chemistry reaction.•Copolymer coatings with antifouling capacity reduce protein adsorption of about 55–60%.•High capturing efficiency of lipidic nanovesicles and 82% of delivery after release.

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关键词

Membrane,Copolymer coating,Peptide conjugation,Filtration,Nanovesicles capture

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