High Dimensional Immune Profiling of Smoldering Multiple Myeloma Distinguishes Distinct Tumor Microenvironments.

Nicolas Fernandez,Deepak Perumal,Adeeb Rahman,Seunghee Kim-Schulze,Jen Yesil,Daniel Auclair,Homer Adams,Samir Parekh,Sacha Gnjatic,Hearn Jay Cho

Clinical lymphoma, myeloma & leukemia（2022）

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摘要

These results suggest that the continuum from MGUS to MM does not consist of a single pathway in the TME, and that complex interactions between myeloma cells and the TME may ultimately determine progression and inform clinical management.

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tumor,immune

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