Potential Mechanisms Involved in Chronic Kidney Disease of Unclear Etiology.

Michael W Holliday,Qingtian Li, Edlyn G Bustamante,Jingbo Niu,Luping Huang, Ilse M Espina, Jose R Dominguez,Luan Truong,Kristy O Murray,Lei Fan,Samaya J Anumudu,Maulin Shah,Rebecca S B Fischer,Chandan Vangala,Sreedhar Mandayam,Jose Perez,Jenny S Pan,Sehrish Ali,Ahmed A Awan,David Sheikh-Hamad

Clinical journal of the American Society of Nephrology : CJASN（2022）

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摘要

Exposure to agrochemicals is associated with Mesoamerican nephropathy, and chronic exposure of mice to paraquat, a prototypical oxidant, induced kidney failure similar to Mesoamerican nephropathy.

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关键词

CKDu,MATE1,Mesoamerican nephropathy,OCT2,ROS,agrochemicals,chronic kidney disease

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