Clinical Characteristics of Children with Cerebral Injury preceding Treatment of Diabetic Ketoacidosis.

Nicole S Glaser,Kimberly S Quayle,Julie K McManemy,Lise E Nigrovic,Leah Tzimenatos,Michael J Stoner,Jonathan E Bennett,Jennifer L Trainor,Arleta Rewers,Jeff E Schunk,Sage R Myers,Maria Y Kwok,Kathleen M Brown,Simona Ghetti,T Charles Casper,Cody S Olsen,Nathan Kuppermann

The Journal of pediatrics（2022）

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摘要

Previous studies have identified more severe acidosis and higher blood urea nitrogen (BUN) as risk factors for cerebral injury during treatment of diabetic ketoacidosis (DKA) in children; however, cerebral injury also can occur before DKA treatment. We found that lower pH and higher BUN levels also were associated with cerebral injury at presentation.

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