Study Design and Rationale for the PACE-LUNG Trial: A Multicenter, Single-Arm, Phase II Clinical Trial Evaluating the Efficacy of Additional Chemotherapy for Patients with EGFRm NSCLC with the Continued Presence of Plasma ctDNA EGFRm at Week 3 After Start of Osimertinib 1st-Line Treatment

Fabian Acker,Lukas Aguinarte, Friederike Althoff,Sophie Heinzen, Maximilian Rost,Peter Wild, Lena Reiser, Martin Mänz,Frauke Meyer,Jan Stratmann,Martin Sebastian

Clinical Lung Cancer(2022)

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摘要
2019-004757-88 (EudraCT).
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关键词
EGFR,EGFRm Clearance,Liquid biopsy,Response-stratified therapy,Treatment escalation
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