The small heat shock protein Hsp12.1 has a major role in the stress response and virulence of Cryptococcus gattii

Heryk Motta,Júlia Catarina Vieira Reuwsaat,Eamim Daidrê Squizani,Matheus da Silva Camargo,Ane Wichine Acosta Garcia,Augusto Schrank,Marilene Henning Vainstein,Charley Christian Staats,Lívia Kmetzsch

Fungal Genetics and Biology（2023）

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摘要

•Small heat shock protein 12.1 absence impairs C. gattii virulence.•Small heat shock protein 12.1 is involved in C. gattii oxidative stress response.•Small heat shock protein 12.1 respond to cell membrane stress in C. gattii.

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关键词

Cryptococcus gattii,Heat shock protein,Hsp12,Plasma membrane,Oxidative stress

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