First report of auxiliary liver transplantation for severe cholangiopathy after SARS‐CoV ‐2 respiratory infection

American Journal of Transplantation(2022)

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摘要
Post-coronavirus disease 2019 (COVID-19) cholangiopathy (PCC) is a new entity observed in patients recovering from severe COVID-19 pneumonia. Most patients recover with cholestasis improving over a period of time. In some patients, cholestasis is severe and persists or progresses to liver failure necessitating liver transplant. We present a previously healthy 50-year-old man who developed PCC with peak total bilirubin of 42.4 mg/dl and did not improve with medical management. He underwent living donor auxiliary right lobe liver transplantation. He recovered well after transplant and remains asymptomatic at 6 months follow-up with good graft function and recovering function in native liver remnant.
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关键词
cholestasis,COVID-19 pneumonia,liver regeneration,living donor liver transplantation,subacute liver failure,therapeutic plasma exchange
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