Efficacy and safety of sequential combination therapy for pulmonary arterial hypertension: A meta-analysis of Randomized-Controlled Trials

Zhen Tan,Pan-Yun Wu,Teng-Teng Zhu,Wen Su,Zhen-Fei Fang

Pulmonary Pharmacology & Therapeutics（2022）

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摘要

For WHO-FC II-III PAH patients who have established BT, our study reinforced the recommendation of SCT to improve clinical worsening, functional status, and exercise capacity, although with higher incidence of side-effects and withdrawal.

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关键词

Pulmonary arterial hypertension,Sequential combination therapy,Background therapy,Randomized controlled trial,Meta-Analysis

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