Reliability of using generic flow conditions to quantify aneurysmal haemodynamics: A comparison against simulations incorporating boundary conditions measured in vivo

•Aneurysmal haemodynamics of 19 patients were quantified by CFD simulations incorporating physiologically real boundary conditions measured in vivo.•Statistically significant difference was found between simulations using generic and patient-specific boundary conditions, in terms of the TAWSS, PIAF, and OSI.•Outflow strategies yielded limited variations to the simulated aneurysmal haemodynamics.•Steady-state CFD using cycle-averaged boundary conditions achieved WSS and PIAF results similar to those obtained from transient simulations.