Metabolic profile and dynamic characteristic of rhubarb during the vitro biotransformation by human gut microbiota

Jing Zhang,Ping Zhou,Yudi Xu, Feng Ji, Xin Zheng,Huaiyou Wang,Yongqing Xiao,Ying Liu

Food Chemistry（2022）

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摘要

•In vitro metabolism of RP and SP extract by human gut microbiota was conducted.•Significant differences were found in metabolic profiles between RP and SP.•Dynamic changes of components confirmed the metabolic differences.•Gut microbiota were associated with different laxative effect of RP and SP.

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关键词

ESI,LOD,LOQ,UHPLC-IT-TOF/MS,OPLS-DA,PCA,QC,TIC,UPLC-QQQ MS/MS

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