LCZ696 (sacubitril/valsartan) protects against cyclophosphamide-induced nephrotoxicity in adult male rats: Up-regulation of Apelin-13/ACE2, miR-200, and down-regulation of TGF-β/SMAD 2/3 and miR-192

Samah S. Abbas,Mona F. Schaalan,Sahar M. Gebril,Fatma E. Hassan,Maha O. Mahmoud,Soha O. Hassanin

Life Sciences（2022）

引用 7|浏览5

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摘要

Effect of LCZ696 (sacubitril/valsartan) in a rat model of cyclophosphamide-induced renal toxicity: apelin-13/ACE2/TGF-β/SMAD2/3 and miRNA-192/200 downstream signaling pathways. Created in BioRender.comUnlabelled Image

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关键词

Cyclophosphamide,Nephrotoxicity,LCZ696,Apelin-13,ACE-2,miR-200/192

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