Cost-Effectiveness of Polygenic Risk Scores to Guide Statin Therapy for Cardiovascular Disease Prevention.

Michel Kiflen,Ann Le,Shihong Mao,Ricky Lali,Sukrit Narula,Feng Xie,Guillaume Paré

Circulation. Genomic and precision medicine（2022）

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摘要

This study suggests that using PRS alongside existing guidelines might be cost-effective for CVD. Stronger predictiveness combined with decreased cost of PRS could further improve cost-effectiveness, providing an economic basis for its inclusion into clinical care.

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关键词

cardiovascular disease,cause of death,lipid,morbidity,risk factors

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