The Relationship Between Grey Matter Volume and Clinical and Functional Outcomes in People at Clinical High Risk for Psychosis.
Schizophrenia bulletin open(2022)
摘要
In CHR individuals, lower striatal GMV was associated with a poor level of overall functioning at follow-up. This finding was not related to effects of antipsychotic or antidepressant medication. The failure to replicate previous associations between GMV and later psychosis onset, despite studying a relatively large sample, is consistent with the findings of recent large-scale multi-center studies.
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关键词
clinical high risk for psychosis,clinical outcomes,functioning,grey matter volume,remission,structural magnetic resonance imaging,transition to psychosis
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