Dysbiosis of the gut microbiota in children with severe motor and intellectual disabilities receiving enteral nutrition: A pilot study.

Yoko Nakai,Shohei Akagawa,Sadayuki Fujishiro,Yuko Akagawa,Mitsuru Yamagishi,Sohsaku Yamanouchi,Takahisa Kimata,Atsushi Ohashi,Masaki Hashiyada,Atsushi Akane,Shoji Tsuji,Kazunari Kaneko

JPEN. Journal of parenteral and enteral nutrition（2023）

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摘要

Children with SMIDs showed dysbiosis with alteration in the microbial diversity, which could partly be attributed to their low dietary fiber intake. Further studies, with the intervention of prebiotics, probiotics, and synbiotics, are warranted to improve dysbiosis in children with SMIDs.

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dysbiosis,enteral nutrition,gut microbiota, 16S rRNA gene sequencing,severe motor and intellectual disability

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