[Study on mechanisms of Th17/Treg imbalance in patients with cystic echinococcosis based on miRNA expression profiles].

D Lu, J H Song, Z J Ma, P Y Zhang, L Xu, C Wei,Y Chen,S Zhou, J F Zhu, Y L Li, J Q Zhao, M X Zhu, R Zhao,H Wang,X J Chen,W Zhao, C Su

Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control（2022）

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摘要

Significant changes are found in serum miRNA expression profiles among patients with infections, and differentially expressed miRNAs may lead to Th17/Treg imbalance through targeting the key transcription factors of Th17/Treg or PI3K-Akt and mTOR pathways, which facilitates the long-term parasitism of in hosts and causes a chronic disease.

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关键词

,Immune imbalance,T helper type 17,microRNA,regulatory T cell

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