Treatment horizon in multiple myeloma.

EUROPEAN JOURNAL OF HAEMATOLOGY(2022)

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摘要
OBJECTIVES:This paper reviews current and emerging therapies for multiple myeloma (MM). METHODS:Narrative review. RESULTS:MM is a complex, heterogenous condition, and in recent years there has been an expansion in the number and range of treatments. Several new treatment approaches, including enhanced monoclonal antibodies, antibody-drug conjugates, bispecific T-cell engagers, and chimeric antigen-T-cell therapy are under development. CONCLUSIONS:The emergence of new treatments that aim to tackle MM-associated immune dysfunction has led to improvements in overall survival.
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关键词
ADC, BiTE, CAR-T celmod, immunotherapy, melflufen, monoclonal antibody, multiple myeloma, selinexor, venetoclax
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