Characterization of Hepatic Dysfunction in Subjects Diagnosed With Chronic GVHD by NIH Consensus Criteria

Alexander H. Yang,Ma Ai Thanda Han,Niharika Samala,Bisharah S. Rizvi,Rachel Marchalik,Ohad Etzion,Elizabeth C. Wright,Liang Cao,Frances T. Hakim, Elizabeth Jones,Devika Kapuria,Dennis D. Hickstein,Daniel Fowler,Jennifer A. Kanakry,Christopher G. Kanakry,David E. Kleiner,Christopher Koh,Steven Z. Pavletic,Theo Heller

Transplantation and Cellular Therapy（2022）

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摘要

•Hepatic chronic GVHD causes significant morbidity and mortality•Low platelets may be associated with progressive liver disease•Current diagnostic criteria for hepatic GVHD have poor performance•Liver biopsy is important to consider given the broad differential•Liver dysfunction due to causes other than hepatic GVHD should be considered

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关键词

Liver dysfunction,Graft-versus-host disease,Hematopoietic stem cell transplantation,Morbidity,Mortality

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