Progression-free survival and quality of life in metastatic breast cancer: The patient perspective

•Overall survival benefit combined with good QoL are the most important endpoints for mBC patients.•Time without disease progression is meaningful to patients when coupled with no worsening in or improvements in QoL.•Quality of life is highly individual and evolves throughout the treatment journey.•Surrogate endpoints are confusing; more patient-centered language is needed.•Healthcare professionals should account for disease and psychological well-being.