Critical Appraisal of Randomized Controlled Trials on Unruptured Brain Arteriovenous Malformations

Anastasia Tasiou,Alexandros G. Brotis,Christos Tzerefos,Xanthoula Lambrianou,Theodosios Spiliotopoulos,Cargill H. Alleyne,Edoardo Boccardi,Bengt Karlsson,Neil Kitchen,Torstein R. Meling,Robert F. Spetzler,Christos M. Tolias,Kostas N. Fountas

World neurosurgery（2022）

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摘要

Our study confirmed the high risk of bias mainly attributed to several protocol violations, deviations, minimal external validity and selection, attrition, and allocation biases of the ARUBA trial. Analysis of the TOBAS trial revealed a moderate overall reporting clarity and a high risk of bias.

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关键词

Brain arteriovenous malformations,CONSORT 2010,Management,Randomized controlled trials,RoB 2,Unruptured

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