Perfluorooctanoic acid (PFOA) exposure affects early embryonic development and offspring oocyte quality via inducing mitochondrial dysfunction

•PFOA exposure has adverse effect on early embryonic development.•PFOA exposure induces mitochondrial dysfunction in 2-cell stage.•PFOA exposure produces excessive ROS to induce the occurrence of autophagy and apoptosis.•Gestational exposure to PFOA has potential toxic effects on ovarian function and lead to a higher incidence of meiotic defects in F1 female offspring.