Haematology laboratory parameters to assess efficacy of CD19-, CD22-, CD33-, and CD123-directed chimeric antigen receptor T-cell therapy in haematological malignancies.

Bradley Drumheller,Kirubel Gebre,Brian Lockhart,Elizabeth Margolskee,Amrom Obstfeld,Michele Paessler,Vinodh Pillai

International journal of laboratory hematology（2022）

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摘要

Autologous and allogeneic CAR T cell therapy produce unique changes in common haematology laboratory parameters and could be a useful surrogate to follow CAR T-cell expansion after infusion.

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关键词

ALC,ALL,AML,CAR T cells,CPD,immunotherapy

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