Ginsenoside Rb1 Reduces D-GalN/LPS-induced Acute Liver Injury by Regulating TLR4/NF-κB Signaling and NLRP3 Inflammasome.

Yimei Liu,Ninghua Liu,Yujing Liu,Hongyu He,Zhe Luo,Wenjun Liu,Nan Song,Minjie Ju

Journal of clinical and translational hepatology（2022）

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摘要

Ginsenoside Rb1 protects mice against D-GalN/LPS-induced ALI by attenuating oxidative stress and the inflammatory response through the TLR4/NF-κB signaling pathway and NLRP3 inflammasome activation.

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关键词

Chemical and drug induced liver injury,Ginsenosides,NLR family, pyrin domain-containing 3 protein,Toll-like receptor 4

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