Accurate, automatic annotation of peptidases with hotpep-protease

Peptidases are essential for intracellular protein processing, signaling and homeostasis, physiological processes and for digestion of food. Moreover, peptidases are important biotechnological enzymes used in processes such as industrial food processing, leather manufacturing and the washing industry. Identification of peptidases is a crucial step in their characterization but peptidase annotation is not a trivial task due to their large sequence diversity.