Findings of 18 F-PI-2620 tau PET imaging in patients with Alzheimer's disease and healthy controls in relation to the plasma P-tau181 levels in a Japanese sample.

Shogyoku Bun,Sho Moriguchi,Toshiki Tezuka,Yoshiaki Sato,Keisuke Takahata,Morinobu Seki,Shinichiro Nakajima,Yasuharu Yamamoto,Yasunori Sano,Natsumi Suzuki,Ayaka Morimoto,Ryo Ueda,Hajime Tabuchi,Daisuke Ito,Masaru Mimura

Neuropsychopharmacology Reports（2022）

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摘要

Our results add to accumulating evidence suggesting that F-PI-2620 is a promising tau PET tracer that allows patients with AD to be distinguished from healthy controls, although a study with a larger sample size is warranted.

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关键词

Alzheimer’s disease,MMSE,plasma p-181,positron emission tomography,tau,tauADAS-cog

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