Synbiotic modulates intestinal microbiota metabolic pathways and inhibits DMH-induced colon tumorigenesis through c-myc and PCNA suppression

Bruna Cristina dos Santos Cruz,Vinícius da Silva Duarte,Roberto Sousa Dias,Andressa Ladeira Bernardes,Sérgio Oliveira de Paula,Célia Lúcia de Luces Fortes Ferreira,Maria do Carmo Gouveia Peluzio

Food Research International（2022）

引用 3|浏览6

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摘要

•Synbiotic reduces the expression of genes related to colorectal carcinogenesis.•Synbiotic modulates functional metabolic pathways of the intestinal microbiota.•Synbiotic VSL#3 and PBY reduces colonic inflammatory response in colon.

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关键词

Probiotic,Prebiotic,Colorectal cancer,Gut microbiota,Dysbiosis

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