Variability of the Cytochrome b Polypeptide in the Gray Red-Backed Vole ( Craseomys rufocanus )

Biology Bulletin(2022)

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摘要
— Based on our own data and that borrowed from available sources, polymorphism of the cytochrome b polypeptide of the gray red-backed vole ( Craseomys rufocanus Sundevall, 1846) is considered in the populations of Northeast Asia. Twenty-seven isoforms of the enzyme amino acid sequence were found. A comparative analysis of the frequencies of the cytochrome b variants was carried out in the samples of the gray red-backed vole. The localization of amino acid substitutions was determined in the model of the secondary structure of the enzyme. The method of TreeSAAP analysis, and Snit’s, Bachinsky’s, and Grantsem’s methods reliably confirm the conservative type of amino acid substitutions, which indicates the effect of stabilizing selection aimed at the preservation of two physicochemical properties in a number of polypeptide variants.
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关键词
gray red-backed vole,Craseomys rufocanus,cytochrome b (cytb) gene,isoforms of the cytochrome b (Cytb) enzyme,genetic diversity,phylogenetic analysis
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