Solvent-antisolvent precipitation in a spinning disc reactor: Precipitation kinetics and mathematical modelling of starch nanoparticles

Sahr Sana, Jamie Manson,Vladimir Zivkovic,Kamelia Boodhoo

Chemical Engineering and Processing - Process Intensification（2022）

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摘要

•Nucleation rate increases with flow rate, disc speed and supersaturation.•Nucleation rates of the order of 1016 mL−1 s − 1 measured on spinning disc.•Higher nucleation rate on a grooved surface at conditions of low shear.•Population balance modelling undertaken for precipitation on a spinning disc.•Modelled data are in good agreement with experimental data.

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关键词

Spinning disc reactor,Process intensification,Starch nanoparticles,Solvent-antisolvent precipitation,Precipitation kinetics,Nucleation rate,Population balance model

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