Preparation of AuNPs/MXene nanocomposite for the electrochemical determination of dopamine

A novel sensing system was constructed by using gold nanoparticles (AuNPs) and MXene-Ti3C2Tx nanocomposite decorated glassy carbon electrode (GCE) for dopamine (DA) determination. The AuNPs/MXene nanocomposite was prepared via a drop coating method, which could appreciably enlarge the electrochemically active surface area of as-prepared sensor and promote electron transfer with the enhanced electrochemical signals. Applying AuNPs/MXene/GCE in the optimum conditions, differential pulse voltammetric (DPV) current responses vs. DA concentrations are linear in the wider range of 2.0-500.0 mu mol/L along with low detection limit of 0.67 mu mol/L (S/N=3). Moreover, the proposed AuNPs/MXene modified GCE exhibited excellent stability, selectivity and reproducibility. Finally, this sensor had been utilized to detect DA successfully in DA hydrochloride injection with satisfactory recoveries, providing a promising application for further sensing analysis.