Correlation analysis of antipsychotic dose and speech characteristics according to extrapyramidal symptoms

In this paper, correlation analysis between speech characteristics and the dose of antipsychotic drugs was performed. To investigate the pattern of speech characteristics of ExtraPyramidal Symptoms (EPS) related to voice change, a common side effect of antipsychotic drugs, a Korean-based extrapyramidal symptom speech corpus was constructed through the sentence development. Through this, speech patterns of EPS and non-EPS groups were investigated, and in particular, a strong speech feature correlation was shown in the EPS group. In addition, it was confirmed that the type of speech sentence affects the speech feature pattern, and these results suggest the possibility of early detection of antipsychotics-induced EPS based on the speech features.