TRIFLIC ACID ADSORBED ON SILICA GEL AS AN EFFICIENT CATALYST FOR O-ISOPROPYLIDENATION OF SUGAR DERIVATIVES

Triflic acid immobilized on silica gel has been identified as an excellent catalyst for the chemoselective O-isopropylidenation of free sugars and functionalized carbohydrates with acetone. This method is simple and economic for large-scale synthesis together with good to excellent yield, low catalyst loading and non-aqueous workup procedure.