Correlation between the Lymphocyte-To-Monocyte Ratio (LMR) and Child-Pugh and MELD/MELDNa Scores in Vietnamese Patients with Liver Cirrhosis

GASTROENTEROLOGY INSIGHTS(2022)

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摘要
Objectives: This study aims to determine cirrhotic patients' clinical and laboratory characteristics, thereby examining the correlation between lymphocyte-to-monocyte ratio and Child-Pugh and MELD/MELDNa scores. Methods: A cross-sectional study with an analysis of 153 patients admitted to the Department of Gastroenterology-Clinical Hematology at Can Tho Central General Hospital. Data were collected via patient interviews and medical records. Results: The included patients were more likely to be male (66.7%) and were >= 60 years old (51.6%). Excessive alcohol consumption and hepatitis B were the dominant causes of cirrhosis (35.3% and 34.0%). The clinical and laboratory characteristics were similar to previous studies in cirrhotic patients. The mean Child score was 9.3 +/- 2.1, including 9.8% of patients with Child A, 44.4% for Child B, and 45.8% for Child C. The mean MELD and MELDNa scores were 16.9 +/- 7.1 and 19.4 +/- 8.1, respectively. The mean lymphocyte-to-monocyte ratio (LMR) is 2.0 +/- 2.2 (from 0.09 to 25.3), being negatively correlated with the other scores (Pearson correlation coefficients were -0.238; -0.211 and -0.245, respectively, all p-values < 0.01). Patients with LMR below 3.31 were more likely to be classified as Child-Pugh B and C. Conclusion: The correlation between LMR with Child-Pugh, MELD, and MELDNa scores was weak and negative.
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关键词
liver cirrhosis, clinical, hematological, LMR, Child-Pugh, model for end-stage liver disease, MELDNa, Vietnamese
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