Synthesis and characterization of Schiff base derivatives and its effect on urinary parameters of Wistar rats: A comparative analysis with different classes of diuretics

Jonathan R. U. Adao,Priscila de Souza,Thaise Boeing, Lusa N. B. Mariano, Ana M. F. Brandt,Johann V. Hemmer,Heitor A. G. Bazani,Sergio F. de Andrade, Rogrio Corra,Luiz C. Klein-Jnior,Rivaldo Niero

Journal of Molecular Structure（2022）

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摘要

•Bidentate Schiff bases (SB) derivates 1, 3, and 4 showed diuretic effect.•SB 1, 3, and 4 induced natriuretic and kaliuretic effects.•SB 1, 3, and 4 revealed a calcium-sparing effect.•SB 1, 3, and 4 decreased the number of calcium oxalate crystals in the urine.

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关键词

Diuresis,Natriuresis,Calcium,Antiurolytic

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