Hair growth-promoting effects of Sargassum glaucescens oligosaccharides extracts

Journal of the Taiwan Institute of Chemical Engineers(2022)

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摘要
•Microwave-assisted high-pressure water enhanced S. glaucescens fucoidan yield•Subcritical water extraction can directly generate oligo-fucoidans.•Fucoidan extracts promoted human follicle dermal papilla cells proliferation.•Fucoidan extracts enhanced IGF-1 and LEF-1 gene expression and promote hair growth.•Low molecular weight fucoidan has hair growth-promoting activity in C57BL/6 mice.
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关键词
Sargassum glaucescens,fucoidan,alopecia,IGF-1,LEF-1
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