Synthesis of fluoro and trifluoromethyl substituents containing novel tetracyclic N-benzylated benzopiperazine fused acridone regioisomers using a greener solvent 2-MeTHF and their DFT studies

Journal of Fluorine Chemistry（2022）

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摘要

•Hazardous solvent free.•Room temperature reaction.•2-MeTHF (Green solvent).•Higher Atom economy.•Higher Yields.

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关键词

Green solvent,N-Benzylation,DFT Studies,Room temperature reaction,synthesis of different regioisomers

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