Exposure to chronic stress impairs the ability to cope with an acute challenge: Modulation by lurasidone treatment

European Neuropsychopharmacology(2022)

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摘要
Chronic stress represents a major contributor for the development of mental illness. This study aimed to investigate how animals exposed to chronic mild stress (CMS) responded to an acute stress (AS), as a vulnerability's challenge, and to establish the potential effects of the antipsychotic drug lurasidone on such mechanisms.
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关键词
Depression,Antipsychotic drug,Lurasidone,Anhedonia,Chronic mild stress,Acute stress
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